On the regulation of T helper type 2 (Th2) responses
"Helper T cells are required for normal immune function and act by marshalling the activity of other immune cell types. Their biology is dominated by a paradigm in which cells adopt mutually antagonistic functional specializations following their activation. One such specialization, adopted by ""T helper type 2 (Th2)"" cells, is characterized by the production of cytokines including IL-4 that drive a response dominated by the production of IgG and IgE antibodies, and the recruitment of innate...[Show more]
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