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The impact of long-interspersed nuclear elements-1 in the mouse genome

Lee, Sung-Hun

Description

Approximately half of the mammalian genome is composed of various types of transposable elements. One class of transposable elements are the LINE-1 elements (long interspersed nucleotide elements) or L1 retrotransposable elements comprising 17% of the human genome and 19% of the mouse genome, respectively. Although most of the LINE-1 retrotransposable elements are in an inactive state, the activation of LINE-1 retrotransposable elements can have an impact on genome stability in various ways,...[Show more]

CollectionsOpen Access Theses
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/150788

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