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Genetic variants experiencing sexually antagonistic selection in humans

Feng, Jinghua

Description

The two sexes are so different that a genetic variant may function differentially in males and females. Because the evolutionary interests of the sexes never exactly coincide and the two sexes share most of their genetic materials (all except the Y chromosome in mammals), conflicting natural selection can arise. Shared variants or traits undergo differential natural selection between the sexes, resulting in selection for a shared trait in one sex displacing the other sex from its optimum. The...[Show more]

CollectionsOpen Access Theses
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/150731

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