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Mechanisms of dexamethasone-induced hypertension

Ong, Sharon Leng Hong

Description

Adrenocortical steroids with predominant glucocorticoid activity, both naturally-occurring and synthetic, have long been recognised as a cause of hypertension. Models of glucocorticoid-induced hypertension (GC-HT) in the rat such as adrenocorticotrophic hormone-induced hypertension (ACTH-HT) and dexamethasone-induced hypertension (DEX-HT) are well-characterised, although the mechanisms contributing to hypertension are less well-understood. Previous studies have shown that ACTH-HT is associated...[Show more]

CollectionsOpen Access Theses
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/150661
DOI: 10.25911/5d5e789f17118

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