Mechanisms of dexamethasone-induced hypertension
Adrenocortical steroids with predominant glucocorticoid activity, both naturally-occurring and synthetic, have long been recognised as a cause of hypertension. Models of glucocorticoid-induced hypertension (GC-HT) in the rat such as adrenocorticotrophic hormone-induced hypertension (ACTH-HT) and dexamethasone-induced hypertension (DEX-HT) are well-characterised, although the mechanisms contributing to hypertension are less well-understood. Previous studies have shown that ACTH-HT is associated...[Show more]
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