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The presentation of multivalent antigens to CD4+ T cells

McNaughton, Euan

Description

Uptake of antigen for processing and presentation on MHC class II molecules is required for initiation of the adaptive immune response. The professional antigen presenting cells (APCs) - dendritic cells (DCs), macrophages and B cells - are responsible for this process. Many of the antigens encountered on the surface of foreign microorganisms are multivalent, such as viral capsid proteins. A great many more are rendered pseudo-multivalent by being held in an array on the cell surface - this...[Show more]

CollectionsOpen Access Theses
Date published: 2010
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/150590
DOI: 10.25911/5d5fc9483cfae
Access Rights: Open Access

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