Identification and characterization of binding sites for NF-kB transcription factors in T cells
Transcription of genes is controlled by trans-acting DNA binding transcription factors interacting with cis-regulatory elements containing their cognate binding sites. The interaction between transcription factors and their binding sites has long been studied to understand transcriptional regulatory networks. Initial studies were performed through in vitro experiments, which have provided insights into transcription factor-DNA interactions and allowed the identification of regulatory elements...[Show more]
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