Skip navigation
Skip navigation

Strain-specific genetic requirements for growth of vaccinia virus in culture

Dobson, Bianca


Poxviruses, including vaccinia virus (VACV), have linear DNA genomes, containing approximately 200 genes. Many of these genes contribute to virulence but are dispensable for replication in tissue culture. To determine whether interactions between these non-essential genes influence vaccinia virus growth in vitro, this thesis focuses on strains of VACV that lack functional copies of multiple genes. Poxvirus genomes are arranged with the highly conserved genes, which are essential for basic...[Show more]

CollectionsOpen Access Theses
Date published: 2014
Type: Thesis (PhD)
DOI: 10.25911/5d611e70a6acd
Access Rights: Open Access


File Description SizeFormat Image
b36002331-Dobson_B.pdf74.51 MBAdobe PDFThumbnail

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator