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Microbiological aspects of Crohn's disease

O'Brien, Claire Louise


Inflammatory Bowel Disease (IBD) is a chronic inflammatory process that affects any part of the gastrointestinal tract in Crohn's disease (CD), or the large intestine in ulcerative colitis. It is thought to result from an ongoing immune response against gut bacteria in genetically susceptible individuals. Putative pathogens, an imbalance of 'good' and 'bad' bacteria, and excessive bacterial translocation have all been implicated. The aim of these studies was to investigate the role of gut...[Show more]

CollectionsOpen Access Theses
Type: Thesis (PhD)


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