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PfATP4 and the biochemical signature of PfATP4-associated compounds

Dennis, Adelaide Sandra Mild


In 2016 more than 200 million cases of malaria were reported and nearly 500 000 people died from the disease. Although there are antimalarial drugs available, the most virulent species of the disease-causing parasite, Plasmodium falciparum, has evolved some level of resistance to many of them. A global effort to accelerate antimalarial drug discovery has led to the finding that one particular parasite protein, the P-type ATPase PfATP4, appears to be the...[Show more]

CollectionsOpen Access Theses
Date published: 2018-01
Type: Thesis (PhD)


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