3D structure determination of a protein in living cells using paramagnetic NMR spectroscopy
Determining the three-dimensional structure of a protein in living cells remains particularly challenging. We demonstrated that the integration of site-specific tagging proteins and GPS-Rosetta calculations provides a fast and effective way of determining the structures of proteins in living cells, and in principle the interactions and dynamics of protein-ligand complexes.
|Collections||ANU Research Publications|
|Source:||Chemical communications (Cambridge, England)|
|Bin-Bin_et_al.pdf||Author/s Accepted Manuscript/ Post-print||496.45 kB||Adobe PDF|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.