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Candidate Sequence Variants for Polyautoimmunity and Multiple Autoimmune Syndrome from a Colombian Genetic Isolate: Implications for Population Genetics

Johar, Angad Singh

Description

Autoimmunity is an immunological disorder whereby patients have lost immunological tolerance to self-antigen. It has extreme financial and socioeconomic burden with costs of over 100 billion dollars in the USA alone, and an estimated prevalence of 9.4%, and evidence indicates that this estimate has increased at a rate of 5% per year for the past 3 years. These phenotypes can be manifested in more severe forms through polyautoimmunity, whereby patients are...[Show more]

CollectionsOpen Access Theses
Date published: 2018
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/148841
DOI: 10.25911/5d611ee691318

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