Skip navigation
Skip navigation

Site-selective tagging of proteins by pnictogen-mediated self-assembly

Nitsche, Christoph; Mahawaththa, Mithun C; Becker, Walter; Otting, Gottfried; Huber, Thomas


Site-selective chemical protein modification is achieved by self-assembly of a specific di-cysteine motif, trivalent pnictogens (As, Sb or Bi) and an aromatic mercaptomethyl-based probe. The strategy is demonstrated with a quaternary complex involving Zika virus protease and a lanthanide ion, enabling paramagnetic nuclear magnetic resonance spectroscopy and luminescence measurements.

CollectionsANU Research Publications
Date published: 2017-10-03
Type: Journal article
Source: Chemical communications
DOI: 10.1039/c7cc06155b
Access Rights: Open Access


File Description SizeFormat Image
ChemCommun2017_53_10894.pdf3.28 MBAdobe PDFThumbnail

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator