Evaluation of the role of innate lymphoid cells following viral vector vaccination
Over the past decade, studies in our laboratory have established that i) compared to systemic route of delivery, mucosal delivery of recombinant fowlpox virus (rFPV) prime can induce excellent high avidity mucosal/systemic HIV-specific CD8+ T cell immunity, ii) this was associated with IL-4/IL-13 cytokine milieu and iii) transient inhibition of IL-13 at the vaccination site can recruit unique lung dendritic cell (DC) subsets, responsible for the induction of...[Show more]
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