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Stereoselective Syntheses of Certain Natural Products and their Analogues from Chiral-pool and Enzymatically-derived Building Blocks

Buckler, Joshua Neil Victor Timshell

Description

This thesis is comprised of six scientific articles and is preceded by an overview that contextualises all of this published/submitted work. The first section of this thesis is comprised of Publications 1-3 and is concerned with the synthesis of novel, oxygenated analogues of the natural and non-natural enantiomeric forms of the Amaryllidaceae alkaloid galanthamine, a reversible and selective acetylcholine esterase (AChE) inhibitor that is used ...[Show more]

CollectionsOpen Access Theses
Date published: 2017
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/146534
DOI: 10.25911/5d650ff8597e1

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