Stereoselective Syntheses of Certain Natural Products and their Analogues from Chiral-pool and Enzymatically-derived Building Blocks
This thesis is comprised of six scientific articles and is preceded by an overview that contextualises all of this published/submitted work. The first section of this thesis is comprised of Publications 1-3 and is concerned with the synthesis of novel, oxygenated analogues of the natural and non-natural enantiomeric forms of the Amaryllidaceae alkaloid galanthamine, a reversible and selective acetylcholine esterase (AChE) inhibitor that is used ...[Show more]
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|Joshua Buckler PhD Thesis Final 2018.pdf||23.79 MB||Adobe PDF|
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