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Enhancing the Steroid Sulfatase Activity of the Arylsulfatase from Pseudomonas aeruginosa

Uduwela, Dimanthi; Pabis, Anna; Stevenson, Bradley; Kamerlin, Shina C. L.; McLeod, Malcolm


Steroidal sulfate esters play a central role in many physiological processes. They serve as the reservoir for endogenous sex hormones and form a significant fraction of the steroid metabolite pool. The analysis of steroid sulfates is thus essential in fields such as medical science and sports drug testing. Although the direct detection of steroid sulfates can be readily achieved using liquid chromatography-mass spectrometry, many analytical approaches, including gas chromatography-mass...[Show more]

CollectionsANU Research Publications
Date published: 2018
Type: Journal article
Source: ACS Catalysis
DOI: 10.1021/acscatal.8b02905
Access Rights: Open Access


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