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Proteolytic processing of platelet receptors

Gardiner, Elizabeth E


Platelets have a major role in hemostasis and an emerging role in biological processes including inflammation and immunity. Many of these processes require platelet adhesion and localization at sites of tissue damage or infection and regulated platelet activation, mediated by platelet adheso-signalling receptors, glycoprotein (GP) Ib-IX-V and GPVI. Work from a number of laboratories has demonstrated that levels of these receptors are closely regulated by metalloproteinases of the A Disintegrin...[Show more]

CollectionsANU Research Publications
Date published: 2018-04
Type: Journal article
Source: Research and practice in thrombosis and haemostasis
DOI: 10.1002/rth2.12096
Access Rights: Open Access


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