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Commentary: Matrix metalloproteinase-13 unlucky for the forming thrombus

Montague, Samantha J; Gardiner, Elizabeth E


Matrix metalloproteinases (MMPs) are calcium‐dependent zinc‐containing endoproteases involved in extracellular matrix and non‐matrix protein degradation.1 In the latest issue of Research and Practice in Thrombosis and Haemostasis, Howes and colleagues2 investigated the role of MMP‐13 in platelet aggregation and thrombus formation and identified that MMP‐13 could engage important platelet receptors and influence platelet function in vitro. MMP‐13 is of great cardiovascular interest as expression...[Show more]

CollectionsANU Research Publications
Date published: 2018-07
Type: Journal article
Source: Research and practice in thrombosis and haemostasis
DOI: 10.1002/rth2.12105
Access Rights: Open Access


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