Higher Serum Immunoglobulin G3 Levels May Predict the Development of Multiple Sclerosis in Individuals With Clinically Isolated Syndrome
Trend, Stephanie; Jones, Anderson P; Cha, Lilian; Byrne, Scott N; Geldenhuys, Sian; Fabis-Pedrini, Marzena J; Carroll, William M; Cole, Judith M; Booth, David R; Lucas, Robyn M; Kermode, Allan G; French, Martyn A; Hart, Prue H
Clinically isolated syndrome (CIS) is a first episode of neurological symptoms that may precede a diagnosis of multiple sclerosis (MS). Therefore, studying individuals with CIS may lead to breakthroughs in understanding the development and pathogenesis of MS. In this study, serum levels of immunoglobulin (Ig)G, IgA, IgM, and IgG1-4 were measured in 20 people with CIS and compared with those in 10 healthy controls (HC) and 8 people with MS. Serum Ig levels in individuals with CIS were compared...[Show more]
|Collections||ANU Research Publications|
|Source:||Frontiers in immunology|
|Access Rights:||Open Access|
|01 Trend S et al Higher serum immunoglobulin 2018.pdf||343.57 kB||Adobe PDF|
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