Skip navigation
Skip navigation

Higher Serum Immunoglobulin G3 Levels May Predict the Development of Multiple Sclerosis in Individuals With Clinically Isolated Syndrome

Trend, Stephanie; Jones, Anderson P; Cha, Lilian; Byrne, Scott N; Geldenhuys, Sian; Fabis-Pedrini, Marzena J; Carroll, William M; Cole, Judith M; Booth, David R; Lucas, Robyn M; Kermode, Allan G; French, Martyn A; Hart, Prue H

Description

Clinically isolated syndrome (CIS) is a first episode of neurological symptoms that may precede a diagnosis of multiple sclerosis (MS). Therefore, studying individuals with CIS may lead to breakthroughs in understanding the development and pathogenesis of MS. In this study, serum levels of immunoglobulin (Ig)G, IgA, IgM, and IgG1-4 were measured in 20 people with CIS and compared with those in 10 healthy controls (HC) and 8 people with MS. Serum Ig levels in individuals with CIS were compared...[Show more]

CollectionsANU Research Publications
Date published: 2018-07-13
Type: Journal article
URI: http://hdl.handle.net/1885/146099
Source: Frontiers in immunology
DOI: 10.3389/fimmu.2018.01590
Access Rights: Open Access

Download

File Description SizeFormat Image
01 Trend S et al Higher serum immunoglobulin 2018.pdf343.57 kBAdobe PDFThumbnail


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator