Dynamic Interplay of Innate and Adaptive Immunity During Sterile Retinal Inflammation: Insights From the Transcriptome
The pathogenesis of many retinal degenerations, such as age-related macular degeneration (AMD), is punctuated by an ill-defined network of sterile inflammatory responses. The delineation of innate and adaptive immune milieu among the broad leukocyte infiltrate, and the gene networks, which construct these responses, are poorly described in the eye. Using photo-oxidative damage in a rodent model of subretinal inflammation, we employed a novel RNA-sequencing framework to map the global gene...[Show more]
|Collections||ANU Research Publications|
|Source:||Frontiers in immunology|
|Access Rights:||Open Access|
|01 Natoli, R et al Dynamic interplay of 2018.pdf||1.02 MB||Adobe PDF|
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