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Modulation of Type-1 and Type-2 Cannabinoid Receptors by Saffron in a Rat Model of Retinal Neurodegeneration

Maccarone, Rita; Rapino, Cinzia; Zerti, Darin; di Tommaso, Monia; Battista, Natalia; Di Marco, Stefano; Bisti, Silvia; Maccarrone, Mauro

Description

Experimental studies demonstrated that saffron (Crocus sativus) given as a dietary supplement counteracts the effects of bright continuous light (BCL) exposure in the albino rat retina, preserving both morphology and function and probably acting as a regulator of programmed cell death [1]. The purpose of this study was to ascertain whether the neuroprotective effect of saffron on rat retina exposed to BCL is associated with a modulation of the endocannabinoid system (ECS). To this aim, we used...[Show more]

CollectionsANU Research Publications
Date published: 2016-11-18
Type: Journal article
URI: http://hdl.handle.net/1885/145900
Source: PloS one
DOI: 10.1371/journal.pone.0166827

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