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Structure and Function of the TIR Domain from the Grape NLR Protein RPV1

Williams, Simon J; Yin, Ling; Foley, Gabriel; Casey, Lachlan W; Outram, Megan A; Ericsson, Daniel J; Lu, Jiang; Boden, Mikael; Dry, Ian B; Kobe, Bostjan


The N-terminal Toll/interleukin-1 receptor/resistance protein (TIR) domain has been shown to be both necessary and sufficient for defense signaling in the model plants flax and Arabidopsis. In examples from these organisms, TIR domain self-association is required for signaling function, albeit through distinct interfaces. Here, we investigate these properties in the TIR domain containing resistance protein RPV1 from the wild grapevine Muscadinia rotundifolia. The RPV1 TIR domain, without...[Show more]

CollectionsANU Research Publications
Date published: 2016-12-08
Type: Journal article
Source: Frontiers in plant science
DOI: 10.3389/fpls.2016.01850
Access Rights: Open Access


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