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Regulation Mechanisms of Peptide Hormones in Neuroendocrine Cancers

Morgan, Jeremy Andrew McInnes


In the work described in this thesis, analytical methods for the detection and quantification of peptide hormones featuring on-line analyte concentration, post-separation tagging and HPLC-fluorescence detection were presented. These methods were used to detect and quantify calcitonin (CT) and its prohormones glycyllysyllysine-extended CT (CTGKK), glycyllysine-extended CT (CTGK) and glycine-extended CT (CT-G) for the first time, in DMS53 small cell lung...[Show more]

CollectionsOpen Access Theses
Date published: 2016
Type: Thesis (PhD)
DOI: 10.25911/5d67b49d648b5


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