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The biological roles of glutathione transferase Omega 1

Menon, Deepthi

Description

Glutathionylation is the reversible redox modification of protein thiols by disulphide formation with glutathione. Glutathionylation can alter protein structure and activity in response to changes in the oxidation state of the protein, thus modulating protein stability. The forward reaction is largely spontaneous while the reverse reaction (deglutathionylation) is predominantly catalysed by the Glutaredoxin (Grx) family of thioltransferases. Glutathione transferase Omega 1 (GSTO1-1) is an...[Show more]

CollectionsOpen Access Theses
Date published: 2015-03
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/14281

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