Development and validation of prognostic nomograms for metastatic gastrointestinal stromal tumour treated with imatinib
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Lee, Chee Khoon; Goldstein, David; Gibbs, Emma; Joensuu, Heikki; Zalcberg, John; Verweij, Jaap; Casali, Paolo G; Maki, Robert G; Cioffi, Angela; McArthur, Grant; Lord, Sarah J; Yip, Desmond; Kanjanapan, Yada; Rutkowski, Piotr
Description
PURPOSE Metastatic gastrointestinal stromal tumour (GIST) is generally an incurable disease with variable response to imatinib. We aimed to develop prognostic nomograms to predict overall survival (OS) and progression-free survival (PFS) for patients treated with imatinib. METHODS Nomograms were developed in a training cohort (n=330) of patients treated in a randomised trial (EORTC-ISG-AGITG 62005 phase III study) using Cox regression models, and validated in patients (n=236) treated in routine...[Show more]
Collections | ANU Research Publications |
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Date published: | 2015-03-19 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/14195 |
Source: | European Journal of Cancer |
DOI: | 10.1016/j.ejca.2015.02.015 |
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