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Development of the Human Fetal Kidney from Mid to Late Gestation in Male and Female Infants

Ryan, Danica; Sutherland, Megan R; Flores, Tracey J; Kent, Alison L; Dahlstrom, Jane; Puelles, Victor G; Bertram, John F; McMahon, Andrew P; Little, Melissa H; Moore, Lynette; Black, Mary Jane


BACKGROUND During normal human kidney development, nephrogenesis (the formation of nephrons) is complete by term birth, with the majority of nephrons formed late in gestation. The aim of this study was to morphologically examine nephrogenesis in fetal human kidneys from 20 to 41weeks of gestation. METHODS Kidney samples were obtained at autopsy from 71 infants that died acutely in utero or within 24h after birth. Using image analysis, nephrogenic zone width, the number of glomerular...[Show more]

CollectionsANU Research Publications
Date published: 2017-12-20
Type: Journal article
Source: EBioMedicine
DOI: 10.1016/j.ebiom.2017.12.016
Access Rights: Open Access


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