The NMR ‘split peak effect’ in cell suspensions: Historical perspective, explanation and applications
The physicochemical environment inside cells is distinctly different from that immediately outside. The selective exchange of ions, water and other molecules across the cell membrane, mediated by integral, membrane-embedded proteins is a hallmark of living systems. There are various methodologies available to measure the selectivity and rates (kinetics) of such exchange processes, including several that take advantage of the non-invasive nature of NMR spectroscopy. A number of solutes,...[Show more]
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|Source:||Progress in Nuclear Magnetic Resonance Spectroscopy|
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