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The NMR ‘split peak effect’ in cell suspensions: Historical perspective, explanation and applications

Kuchel, Philip W.; Kirk, Kiaran; Shishmarev, Dmitry


The physicochemical environment inside cells is distinctly different from that immediately outside. The selective exchange of ions, water and other molecules across the cell membrane, mediated by integral, membrane-embedded proteins is a hallmark of living systems. There are various methodologies available to measure the selectivity and rates (kinetics) of such exchange processes, including several that take advantage of the non-invasive nature of NMR spectroscopy. A number of solutes,...[Show more]

CollectionsANU Research Publications
Date published: 2018
Type: Journal article
Source: Progress in Nuclear Magnetic Resonance Spectroscopy
DOI: 10.1016/j.pnmrs.2017.11.002


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