Skip navigation
Skip navigation

Photobiomodulation with 670 nm light ameliorates Müller cell-mediated activation of microglia and macrophages in retinal degeneration

Lu, Yen-Zhen; Natoli, Riccardo; Madigan, Michele; Fernando, Nilisha; Saxena, Kartik; Aggio-Bruce, Riemke; Jiao, Haihan; Provis, Jan; Valter, Krisztina

Description

Müller cells, the supporting cells of the retina, play a key role in responding to retinal stress by releasing chemokines, including CCL2, to recruit microglia and macrophages (MG/MΦ) into the damaged retina. Photobiomodulation (PBM) with 670 nm light has been shown to reduce inflammation in models of retinal degeneration. In this study, we aimed to investigate whether 670 nm light had an effect on Müller cell-initiated inflammation under retinal photo-oxidative damage (PD) in vivo and...[Show more]

CollectionsANU Research Publications
Date published: 2017
Type: Journal article
URI: http://hdl.handle.net/1885/139083
Source: Experimental eye research
DOI: 10.1016/j.exer.2017.09.002

Download

File Description SizeFormat Image
1-s2.0-S0014483517304475-main.pdf2.85 MBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  23 August 2018/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator