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Gastrointestinal perforation in metastatic colorectal cancer patients with peritoneal metastases receiving bevacizumab

Roohullah, Aflah; Wong, Hui-Li; Sjoquist, Katrin M; Gibbs, Peter; Field, Kathryn; Tran, Ben; Shapiro, Jeremy; Mckendrick, Joe; Yip, Desmond; Nott, Louise; Gebski, Val; Ng, Weng; Chua, Wei; Price, Timothy; Tebbutt, Niall; Chantrill, Lorraine


AIM To investigate the safety and efficacy of adding bevacizumab to first-line chemotherapy in metastatic colorectal cancer patients with peritoneal disease. METHODS We compared rates of gastrointestinal perforation in patients with metastatic colorectal cancer and peritoneal disease receiving first-line chemotherapy with and without bevacizumab in three distinct cohorts: (1) the AGITG MAX trial (Phase III randomised clinical trial comparing capecitabine vs capecitabine and bevacizumab vs...[Show more]

CollectionsANU Research Publications
Date published: 2015-05-07
Type: Journal article
Source: World journal of gastroenterology:WJG
DOI: 10.3748/wjg.v21.i17.5352


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