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Dynamics of evoked and spontaneous calcium transients in synaptic boutons of neocortical pyramidal neurons

Tran, Le Thuy Van


In response to an action potential (AP), a transient rise in the intracellular calcium concentration ([Ca2+]i) causes transmitter release from nerve terminals. As the spatiotemporal dynamics of this calcium rise can affect the efficacy and plasticity of synaptic connections, it is essential to understand their determinants. To characterise factors that shape calcium transients in neocortical synaptic boutons, layer 5 pyramidal cells in the rat somatosensory cortex were filled through the patch...[Show more]

CollectionsOpen Access Theses
Date published: 2017
Type: Thesis (PhD)
DOI: 10.25911/5d70f0689924c


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