Paternal X inactivation does not correlate with X chromosome evolutionary strata in marsupials
BACKGROUND: X chromosome inactivation is the transcriptional silencing of one X chromosome in the somatic cells of female mammals. In eutherian mammals (e.g. humans) one of the two X chromosomes is randomly chosen for silencing, with about 15% (usually in younger evolutionary strata of the X chromosome) of genes escaping this silencing. In contrast, in the distantly related marsupial mammals the paternally derived X is silenced, although not as completely as the eutherian X. A chromosome wide...[Show more]
|Collections||ANU Research Publications|
|Source:||BMC Evolutionary Biology|
|Rodriguez-Delgado et al Paternal X inactivation 2014.pdf||660.18 kB||Adobe PDF|
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