Expression of TCR-Vβ peptides by murine bone marrow cells does not identify T-cell progenitors
Germline transcription has been described for both immunoglobulin and T-cell receptor (TCR) genes, raising questions of their functional significance during haematopoiesis. Previously, an immature murine T-cell line was shown to bind antibody to TCR-Vβ8.2 in absence of anti-Cβ antibody binding, and an equivalent cell subset was also identified in the mesenteric lymph node. Here, we investigate whether germline transcription and cell surface Vβ8.2 expression could therefore represent a potential...[Show more]
|Collections||ANU Research Publications|
|Source:||Journal of Cellular and Molecular Medicine|
|Abbey et al Expression of TCR-Vβ Peptides 2015.pdf||834.79 kB||Adobe PDF|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.