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Macrophages, cytokines and complement as therapeutic targets in retinal degeneration

Fernando, Nilisha


Age-related macular degeneration (AMD) is the leading cause of blindness amongst the Western population, with an annual cost of 350 billion dollars worldwide. This disease affects a specialised region in the central retina, the macula, where photoreceptors and the retinal pigment epithelium (RPE) cells begin to degenerate upon the onset of AMD. In the more prevalent atrophic or ‘dry’ form of AMD, gradual photoreceptor and RPE cell death leads to the formation...[Show more]

CollectionsOpen Access Theses
Date published: 2017
Type: Thesis (PhD)
DOI: 10.25911/5d70f220802ab


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