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Friend or foe: endoplasmic reticulum protein 29 (ERp29) in epithelial cancer

Chen, Shaohua; Zhang, Daohai


The endoplasmic reticulum (ER) protein 29 (ERp29) is a molecular chaperone that plays a critical role in protein secretion from the ER in eukaryotic cells. Recent studies have also shown that ERp29 plays a role in cancer. It has been demonstrated that ERp29 is inversely associated with primary tumor development and functions as a tumor suppressor by inducing cell growth arrest in breast cancer. However, ERp29 has also been reported to promote epithelial cell morphogenesis, cell survival against...[Show more]

CollectionsANU Research Publications
Date published: 2015
Type: Journal article
Source: FEBS Open Bio
DOI: 10.1016/j.fob.2015.01.004


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