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Novel NF-kB mutations in common variable immunodeficiency (CVID)

Lee, Eunhee


Common variable immunedeficiency (CVID) is the most common symptomatic primary immunodeficiency. The cardinal manifestations are hypogammaglobulinaemia and recurrent infections. In fact, CVID is a heterogeneous cluster of disorders associated with not only infection but also autoimmune disease, sarcoidosis-like granulomatous inflammation, and neoplasia. In a minority of cases, CVID follows simple Mendelian inheritance, and in other cases, there is familial...[Show more]

CollectionsOpen Access Theses
Date published: 2016
Type: Thesis (PhD)
Embargoed until: 2018-10-03


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