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Expression mechanisms underlying different forms of hippocampal long-term potentiation

Johnstone, Victoria Philippa Anne

Description

Long-term potentiation (LTP) in the hippocampus is a model system for investigating the mechanisms of synaptic plasticity and its role in learning and memory in the brain. Progress in understanding the mechanisms responsible for LTP has been somewhat hampered by the existence of multiple LTP variants, even at a single set of synapses. Three discrete forms of LTP (LTP1,2 and 3) that differ in their persistence and the calcium signals required for their induction have recently been characterised...[Show more]

CollectionsOpen Access Theses
Date published: 2011-06
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/12677

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