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Genetics of non-syndromic childhood obesity and the use of high-throughput DNA sequencing technologies

da Fonseca, Ana Carolina Proença; Mastronardi, Claudio; Johar, Angad; Arcos-Burgos, Mauricio; Paz-Filho, Gilberto


BACKGROUND Childhood obesity is a serious public health problem associated with the development of several chronic diseases, such as type 2 diabetes mellitus, dyslipidemia, and hypertension. The elevated prevalence of obesity is mostly due to inadequate diet and lifestyle, but it is also influenced by genetic factors. OBJECTIVES To review recent advances in the field of the genetics of obesity. We summarize the list of genes associated with the rare non-syndromic forms of obesity, and explain...[Show more]

CollectionsANU Research Publications
Date published: 2017-06-16
Type: Journal article
Source: Journal of diabetes and its complications
DOI: 10.1016/j.jdiacomp.2017.04.026


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