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Applying a cumulative deficit model of frailty to dementia: progress and future challenges

Dixon, Roger A; Anstey, Kaarin


The article by Song and colleagues presents findings from the Canadian Study of Health and Aging showing that the accumulation of health deficits, defined dichotomously and unqualified by severity or domain, predicted late-life dementia independent of chronological age. We identify strengths of this model, and also areas for future research. Importantly, this article broadens the perspective of research into measuring risk of dementia from focusing on specific neuropathological markers of...[Show more]

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
Source: Alzheimer's Research & Therapy (2014): 6:84
DOI: 10.1186/s13195-014-0084-z


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