Skip navigation
Skip navigation

Renin–Angiotensin system genetic polymorphisms and brain white matter lesions in older Australians

Assareh, Amelia A.; Mather, Karen A.; Crawford, John D.; Wen, Wei; Easteal, Simon; Tan, Xiaoyun; Mack, Holly A.; Kwok, John B.J.; Schofield, Peter R.; Sachdev, Perminder S.; Anstey, Kaarin


background White matter lesions (WMLs), seen as hyperintensities on T2-weighted magnetic resonance imaging brain scans, are common in the brains of healthy older individuals. They are thought to be related to cerebral small vessel disease and to have a genetic component to their aetiology, and hypertension is thought to be an important risk factor. Genetic polymorphisms in hypertension-related genes may therefore be associated with the formation of WMLs. methods In this study, a sample...[Show more]

CollectionsANU Research Publications
Date published: 2014-08
Type: Journal article
Source: American Journal of Hypertension, 27.9 (2014): 1191-1198
DOI: 10.1093/ajh/hpu035


There are no files associated with this item.

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator