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Diseases associated with general amino acid transporters of the solute carrier 6 family (SLC6)

Bröer, Stefan


Amino acid transporters of the SLC6 family mediate the Na⁺-dependent uptake of neutral amino acids into neurons and epithelial cells of the intestine, kidney and other organs. They are integral parts of amino acid homeostasis in the whole body and the brain. In the intestine they are involved in protein absorption, while in the kidney they regulate plasma amino acid concentrations through reabsorption. The metabolic role of SLC6 amino acid transporters in the brain is less clear and most likely...[Show more]

CollectionsANU Research Publications
Date published: 2013-07
Type: Journal article
Source: Current Molecular Pharmacology 6. 2 (2013): 74-87
DOI: 10.2174/18744672113069990034


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