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False discovery rate control in magnetic resonance imaging studies via Markov random fields

Nguyen, Hien D; McLachlan, Geoffrey J; Cherbuin, Nicolas; Janke, Andrew L


Magnetic resonance imaging (MRI) is widely used to study population effects of factors on brain morphometry. Inference from such studies often require the simultaneous testing of millions of statistical hypotheses. Such scale of inference is known to lead to large numbers of false positive results. Control of the false discovery rate (FDR) is commonly employed to mitigate against such outcomes. However, current methodologies in FDR control only account for the marginal significance...[Show more]

CollectionsANU Research Publications
Date published: 2014-05-07
Type: Journal article
Source: IEEE Transactions on Medical Imaging PP. 99 (2014): 1-15
DOI: 10.1109/TMI.2014.2322369


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