DNA methylation, epialleles and gene regulation: Insights from the honey bee
The development of a multicellular organism is dependent upon interactions between the underlying genetic sequence, epigenomic processes and environmental cues. These interactions are complex, and understanding the exact role that each plays in directing transcription remains difficult. One of the more well studied epigenomic modifications, cytosine DNA methylation, plays a fundamental role in modulating gene activity. This modification has primarily been...[Show more]
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