The Role of Tumour Necrosis Factor in Pulmonary Viral Infections
Tumour necrosis factor (TNF) is a key inflammatory cytokine. Excessive production of TNF is detrimental and associated with chronic inflammatory disorders and severe immunopathology observed in acute infections. TNF plays an important antimicrobial role in the host response to infection but there is contradicting evidence regarding its role in defence against viral infections. Nonetheless, many viruses counter the host immune response by targeting the TNF pathway, indicating an important role...[Show more]
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