Skip navigation
Skip navigation
Open Research will be down for maintenance between 8:00 and 8:15 am on Tuesday, December 1 2020.

GMP Synthase Is Required for Virulence Factor Production and Infection by Cryptococcus neoformans

Chitty, Jessica L.; Tatzenko, Tayla L.; Williams, Simon; Koh, Y. Q. Andre E.; Corfield, Elizabeth C.; Butler, Mark S.; Robertson, Avril A. B.; Cooper, Matthew A.; Kappler, Ulrike; Kobe, Bostjan; Fraser, James A.

Description

Over the last four decades the HIV pandemic and advances in medical treatments that also cause immunosuppression have produced an ever-growing cohort of individuals susceptible to opportunistic pathogens. Of these, AIDS patients are particularly vulnerable to infection by the encapsulated yeast Cryptococcus neoformans Most commonly found in the environment in purine-rich bird guano, C. neoformans experiences a drastic change in nutrient availability during host infection, ultimately...[Show more]

CollectionsANU Research Publications
Date published: 2017-02-17
Type: Journal article
URI: http://hdl.handle.net/1885/116304
Source: The Journal of biological chemistry
DOI: 10.1074/jbc.M116.767533
Access Rights: Open Access

Download

File Description SizeFormat Image
01_GMP_Synthase_2017.pdf1.33 MBAdobe PDFThumbnail


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator