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F-18-florbetaben A beta imaging in mild cognitive impairment

Ong, Kevin; Villemagne, Victor L.; Bahar-Fuchs, Alex; Lamb, Fiona; Chetelat, Gael; Raniga, Parnesh; Mulligan, Rachel S.; Salvado, Olivier; Putz, Barbara; Roth, Katrin; Masters, Colin L.; Reininger, Cornelia B.; Rowe, Christopher C.


F-florbetaben and positron emission tomography were used to examine the relationships between b-amyloid (Ab) deposition, cognition, hippocampal volume, and white matter hyperintensities in mild cognitive impairment (MCI).Methods: Forty-five MCI participants were evaluated. A neocortical standardized uptake value ratio threshold ≥ 1.45 was used to discriminate high from low Ab burden. Correlations were adjusted for age, gender and years of education.Results: High A b burden was found in 53%...[Show more]

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
Source: Alzheimer’s Research & Therapy 5.1 (2013)
DOI: 10.1186/alzrt158


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