Controlling false discovery rates in RNA-Sequencing data
High throughput sequencing technologies are supplanting microarrays as the preferred technology for detecting and quantifying differential gene expression. The raw data produced by the a technique known as RNA-sequencing (RNA-seq), consists of integer counts of reverse transcribed cDNA fragment reads mapped onto each gene or transcript isoform in a reference genome or transcriptome. Many software packages exist for analysing RNA-seq datasets consisting of tables of mapped read counts from...[Show more]
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