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Hydrogen peroxide thermochemical oscillator as driver for primordial RNA replication

Ball, Rowena; Brindley, John


This paper presents and tests a previously unrecognised mechanism for driving a replicating molecular system on the prebiotic earth. It is proposed that cell-free RNA replication in the primordial soup may have been driven by self-sustained oscillatory thermochemical reactions. To test this hypothesis a well-characterised hydrogen peroxide oscillator was chosen as the driver and complementary RNA strands with known association and melting kinetics were used as the substrate. An open flow system...[Show more]

CollectionsANU Research Publications
Date published: 2014-03
Type: Journal article
Source: Interface (2014)
DOI: 10.1098/rsif.2013.1052


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