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Differences in the symptom profile of methamphetamine-related psychosis and primary psychotic disorders

McKetin, Rebecca; Baker, Amanda L; Dawe, Sharon; Voce, Alexandra; Lubman, Dan I

Description

We examined the lifetime experience of hallucinations and delusions associated with transient methamphetamine-related psychosis (MAP), persistent MAP and primary psychosis among a cohort of dependent methamphetamine users. Participants were classified as having (a) no current psychotic symptoms, (n=110); (b) psychotic symptoms only when using methamphetamine (transient MAP, n=85); (c) psychotic symptoms both when using methamphetamine and when abstaining from methamphetamine (persistent MAP,...[Show more]

dc.contributor.authorMcKetin, Rebecca
dc.contributor.authorBaker, Amanda L
dc.contributor.authorDawe, Sharon
dc.contributor.authorVoce, Alexandra
dc.contributor.authorLubman, Dan I
dc.date.accessioned2017-04-11T02:06:01Z
dc.identifier.issn0165-1781
dc.identifier.urihttp://hdl.handle.net/1885/114532
dc.description.abstractWe examined the lifetime experience of hallucinations and delusions associated with transient methamphetamine-related psychosis (MAP), persistent MAP and primary psychosis among a cohort of dependent methamphetamine users. Participants were classified as having (a) no current psychotic symptoms, (n=110); (b) psychotic symptoms only when using methamphetamine (transient MAP, n=85); (c) psychotic symptoms both when using methamphetamine and when abstaining from methamphetamine (persistent MAP, n=37), or (d) meeting DSM-IV criteria for lifetime schizophrenia or mania (primary psychosis, n=52). Current psychotic symptoms were classified as a score of 4 or more on any of the Brief Psychiatric Rating Scale items of suspiciousness, hallucinations or unusual thought content in the past month. Lifetime psychotic diagnoses and symptoms were assessed using the Composite International Diagnostic Interview. Transient MAP was associated with persecutory delusions and tactile hallucinations (compared to the no symptom group). Persistent MAP was additionally associated with delusions of reference, thought interference and complex auditory, visual, olfactory and tactile hallucinations, while primary psychosis was also associated with delusions of thought projection, erotomania and passivity. The presence of non-persecutory delusions and hallucinations across various modalities is a marker for persistent MAP or primary psychosis in people who use methamphetamine.
dc.description.sponsorshipThe research was funded by the National Health and Medical Research Council (Project Grant no. 350974) and the Australian Government Department of Health and Ageing.
dc.format6 pages
dc.format.mimetypeapplication/pdf
dc.publisherElsevier
dc.rights© 2017 Published by Elsevier Ireland Ltd.
dc.sourcePsychiatry research
dc.subjectamphetamine
dc.subjectamphetamine-related disorders
dc.subjectcentral nervous system stimulants
dc.subjecthallucinations
dc.subjectparanoia
dc.subjectpsychotic disorders
dc.subjectstreet drugs
dc.titleDifferences in the symptom profile of methamphetamine-related psychosis and primary psychotic disorders
dc.typeJournal article
local.identifier.citationvolume251
dcterms.dateAccepted2017-02-12
dc.date.issued2017-05
local.publisher.urlhttps://www.elsevier.com/
local.type.statusPublished Version
local.contributor.affiliationMcKetin, Rebecca, Centre for Research on Ageing Health and Wellbeing, CMBE Research School of Population Health, The Australian National University
local.description.embargo2037-12-31
dc.relationhttp://purl.org/au-research/grants/nhmrc/350974
local.identifier.essn1872-7123
local.bibliographicCitation.startpage349
local.bibliographicCitation.lastpage354
local.identifier.doi10.1016/j.psychres.2017.02.028
dcterms.accessRightsOpen Access
CollectionsANU Research Publications

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