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Mechanisms by which obesity accelerates hepatocarcinogenesis: molecular studies in foz/foz mice



Hepatocellular carcinoma (HCC) is the second most common fatal cancer worldwide and the fastest increasing cause of cancer death in Australia. Epidemiological data indicate that obesity and diabetes are independent risk factors. This may be driven by the development of non-alcoholic fatty liver disease (NAFLD), but the molecular mechanisms driving such promotion of hepatocarcinogenesis are unclear. This thesis focuses on the potential role of obesity-related metabolic signalling pathways to...[Show more]

CollectionsOpen Access Theses
Date published: 2016
Type: Thesis (PhD)
DOI: 10.25911/5d74e57aa8ffb


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