Advances in biological dosimetry
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Ivashkevich, A; Ohnesorg, T; Sparbier, C E; Elsaleh, H
Description
Rapid retrospective biodosimetry methods are essential for the fast triage of persons occupationally or accidentally exposed to ionizing radiation. Identification and detection of a radiation specific molecular ‘footprint’ should provide a sensitive and reliable measurement of radiation exposure. Here we discuss conventional (cytogenetic) methods of detection and assessment of radiation exposure in comparison to emerging approaches such as gene expression signatures and DNA damage markers....[Show more]
dc.contributor.author | Ivashkevich, A | |
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dc.contributor.author | Ohnesorg, T | |
dc.contributor.author | Sparbier, C E | |
dc.contributor.author | Elsaleh, H | |
dc.date.accessioned | 2017-03-28T22:49:36Z | |
dc.date.available | 2017-03-28T22:49:36Z | |
dc.identifier.issn | 1742-6588 | |
dc.identifier.uri | http://hdl.handle.net/1885/114095 | |
dc.description.abstract | Rapid retrospective biodosimetry methods are essential for the fast triage of persons occupationally or accidentally exposed to ionizing radiation. Identification and detection of a radiation specific molecular ‘footprint’ should provide a sensitive and reliable measurement of radiation exposure. Here we discuss conventional (cytogenetic) methods of detection and assessment of radiation exposure in comparison to emerging approaches such as gene expression signatures and DNA damage markers. Furthermore, we provide an overview of technical and logistic details such as type of sample required, time for sample preparation and analysis, ease of use and potential for a high throughput analysis. | |
dc.format | 5 pages | |
dc.format.mimetype | application/pdf | |
dc.publisher | IOP Publishing | |
dc.rights | Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. | |
dc.source | Journal of Physics: Conference Series | |
dc.subject | biodosimetry | |
dc.subject | retrospective | |
dc.subject | fast | |
dc.subject | triage | |
dc.subject | occupationally | |
dc.subject | accidentally | |
dc.subject | ionizing | |
dc.subject | radiation | |
dc.title | Advances in biological dosimetry | |
dc.type | Journal article | |
local.identifier.citationvolume | 777 | |
dc.date.issued | 2017 | |
local.publisher.url | http://conferenceseries.iop.org | |
local.type.status | Published Version | |
local.contributor.affiliation | Ivashkevich, Alesia, Genome Sciences, CMBE John Curtin School of Medical Research, The Australian National University | |
local.identifier.essn | 1742-6596 | |
local.bibliographicCitation.issue | 1 | |
local.bibliographicCitation.startpage | 012012 | |
local.identifier.doi | 10.1088/1742-6596/777/1/012012 | |
dcterms.accessRights | Open Access | |
Collections | ANU Research Publications |
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Ivashkevich A et al Advances in biological 2017.pdf | 224.5 kB | Adobe PDF |
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