New evidence for endemic circulation of Ross River virus in the Pacific Islands and the potential for emergence
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Lau, Colleen; Aubry, Maite; Musso, Didier; Teissier, Anita; Paulous, Sylvie; Desprès, Philippe; de-Lamballerie, Xavier; Pastorino, Boris; Cao-Lormeau, Van-Mai; Weinstein, Philip
Description
OBJECTIVES An epidemic of Ross River virus (RRV) occurred in the South Pacific in 1979-1980, but RRV has not been thought to occur endemically outside Australia and Papua New Guinea. A seroprevalence study was conducted to determine whether RRV has circulated in American Samoa since 1980. METHODS RRV ELISA IgG was performed on 200 serum samples collected in American Samoa in 2010; seroneutralization tests were performed on 60 representative samples. RESULTS Of 196 available ELISA IgG results,...[Show more]
dc.contributor.author | Lau, Colleen | |
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dc.contributor.author | Aubry, Maite | |
dc.contributor.author | Musso, Didier | |
dc.contributor.author | Teissier, Anita | |
dc.contributor.author | Paulous, Sylvie | |
dc.contributor.author | Desprès, Philippe | |
dc.contributor.author | de-Lamballerie, Xavier | |
dc.contributor.author | Pastorino, Boris | |
dc.contributor.author | Cao-Lormeau, Van-Mai | |
dc.contributor.author | Weinstein, Philip | |
dc.date.accessioned | 2017-03-21T01:21:09Z | |
dc.date.available | 2017-03-21T01:21:09Z | |
dc.identifier.issn | 1201-9712 | |
dc.identifier.uri | http://hdl.handle.net/1885/113458 | |
dc.description.abstract | OBJECTIVES An epidemic of Ross River virus (RRV) occurred in the South Pacific in 1979-1980, but RRV has not been thought to occur endemically outside Australia and Papua New Guinea. A seroprevalence study was conducted to determine whether RRV has circulated in American Samoa since 1980. METHODS RRV ELISA IgG was performed on 200 serum samples collected in American Samoa in 2010; seroneutralization tests were performed on 60 representative samples. RESULTS Of 196 available ELISA IgG results, 145 (74%, 95% confidence interval 67-80%) were seropositive. Of the 60 samples subjected to seroneutralization testing, none of the 15 ELISA IgG-negative and 16 of the 45 ELISA IgG-positive samples neutralized RRV. ELISA IgG seroprevalence was higher in persons born before/during the 1979-1980 RRV outbreak (78.3%), but was also high (63.0%) in people born after the outbreak who had lived their entire lives in American Samoa. CONCLUSIONS This study provides serological evidence that RRV circulation is likely to have occurred in American Samoa after 1980. Considering there are no marsupials in American Samoa, this finding implies that other species are capable of acting as reservoir hosts and indicates the potential for RRV to circulate in a much wider area than those currently recognized. | |
dc.description.sponsorship | CL was supported by an Australian National Health and Medical Research Council Fellowship (grant number 1109035). | |
dc.format | 4 pages | |
dc.format.mimetype | application/pdf | |
dc.publisher | Elsevier | |
dc.rights | © 2017 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by- nc-nd/4.0/). | |
dc.source | International journal of infectious diseases | |
dc.subject | arboviruses | |
dc.subject | ecology | |
dc.subject | emerging infectious diseases | |
dc.subject | epidemiology | |
dc.subject | Pacific Islands | |
dc.subject | river virus | |
dc.title | New evidence for endemic circulation of Ross River virus in the Pacific Islands and the potential for emergence | |
dc.type | Journal article | |
local.identifier.citationvolume | 57 | |
dcterms.dateAccepted | 2017-01-31 | |
dc.date.issued | 2017-04 | |
local.publisher.url | https://www.elsevier.com/ | |
local.type.status | Published Version | |
local.contributor.affiliation | Lau, Colleen, Department of Global Health, CMBE Research School of Population Health, The Australian National University | |
dc.relation | http://purl.org/au-research/grants/nhmrc/1109035 | |
local.identifier.essn | 1878-3511 | |
local.bibliographicCitation.startpage | 73 | |
local.bibliographicCitation.lastpage | 76 | |
local.identifier.doi | 10.1016/j.ijid.2017.01.041 | |
dcterms.accessRights | Open Access | |
Collections | ANU Research Publications |
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